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36 series

Newt and Demon

Edwin M. Griffiths

B61/100
When the dying Earth finally ends, a mysterious entity grants Theo Spencer the gift of reincarnation — a quiet life as an alchemist. He awakens in a non-human body in the small, swamp-side town of Broken Tusk in the southern reaches of a small kingdom. Broken Tusk doesn't seem like much, but Theo's legendary alchemy skills will soon turn their fortune. A cozy, low-stakes story of town building, charming characters, and alchemy — with no combat and no bad vibes from start to finish.
Goodreads4.36· 1.1K
AlchemyBase BuildingCozyMerchantNon-human MCReincarnation

Blueprint for Immortality: a Crafting Xianxia

NoDragons

B60/100
Booker has woken up in the wrong body — one ruined by drug use, trapped in a dead-end life as the lowest possible apprentice in a massive sect. But that doesn't faze him. When he looks at the mountains, he sees a climb waiting. Better yet, he carries the assistance of a magical book that lets him craft any pill in existence perfectly — a skill alchemists would fight and die for. With his crafting skills, patient soul, and relentlessly upbeat attitude, Booker sets out to climb the first of many mountains. A slow-life xianxia with a focus on crafting and character-driven exploration of the genre's world and people.
Royal Road4.51· 988
AlchemyBase BuildingCozyCraftingCrafting PowerCultivation+6

Rebirth as a Wind Cultivator

Erios909

C59/100
When Li Mei dies in a traffic accident after another soul-crushing retail shift, she awakens inside her favorite game, Phoenix Kingdom Chronicles — inhabiting the body of Lin Xiulan, the scorned second daughter of a noble family. Armed with knowledge of the game and hard-won experience dealing with difficult people, Xiulan refuses to be the family's punching bag. She must master alchemy, tame spirit beasts, and perfect martial arts while fending off scheming sisters and a manipulative stepmother. She also carries knowledge of a devastating future that threatens the entire realm — and surviving her own family long enough to act on it will be the first challenge.
Royal Road4.53· 919
AlchemyCultivationIsekaiOverpowered MCReincarnationWeak to Strong+1

The Nine Tails of Alchemy

Taniko K Williams

C57/100
The year is 2375. With the world drained of natural resources, the government places those deemed of low economic value into cryogenic sleep, their minds connected to virtual worlds as digital citizens. Kadia Greene had no interest in virtual worlds — she was top of her class and on the fast track to university. When she is horrified to receive a notice of digitalization, her life begins to fall apart. But as she enters Kaledon, the newest and most realistic fantasy world on the market, Kadia finds her dreams and passion rekindled. A slice-of-life story following the struggles and successes of a Kitsune protagonist, with a focus on alchemy and crafting.
Goodreads4.35· 741
AlchemyCrafting PowerGameLitNon-human MCVRMMO

Alchemist of the Wilds: An Ex-Assassin's Guide to Cozy Romantic Brews

AT Valentine

C55/100
Lianthorn Belladonna could have been so many things — an artist, a mage, a gardener. Instead, his family sealed his future, trapping him in a life of scheming, poison, and murder. On the cusp of completing his poisonous masterpiece, he makes a choice that changes everything. He flees the gilded cage of their family manor and seeks refuge in a quiet frontier town, where the name Belladonna means nothing. With his family's infamous scarlet-bound recipe book hidden away, he attempts to forget the toxins and discover the simple joy of helping people. Out on the frontier — and in the company of a red-scaled Draconian carpenter with fire powers — 'helping people' will require all his skills, including the alchemy he worked so hard to escape.
Royal Road4.62· 605Goodreads4.40· 50
AlchemyComedyCozyGenius MCNon-human MCOverpowered MC+3

The Emperor Without An Empire

Drew Royston

C52/100
They stole his empire, his cultivation, even his name. Their mistake was leaving him alive. Now going by Shen Taros, he carries seven hundred years of experience in an eighteen-year-old body with the spiritual capacity of wet parchment. A god-like cultivator will hunt him within the year. In the meantime, he is opening meridians one painful breath at a time, learning alchemy from a terrifying mistress, and picking entirely avoidable fights with powerful people who consider themselves beyond justice. Between all of that, working in a decrepit fish warehouse, and dodging loan sharks, he is making remarkable progress. They wanted this Emperor permanently retired. He intends to disappoint them.
Royal Road4.64· 107
AlchemyBase BuildingCraftingCultivationIsekaiLitRPG+3

Department of Dungeon Studies

JPwrites

C47/100
Nox is an alchemist by trade, but he dreams of magehood. Fate dealt him unfavorable cards, yet he has learned to compensate with scholarly pursuits, tenacity, and sheer grit — qualities that catch the attention of Woodson University's scouts. The Department of Dungeon Studies values the mind and its ability to overcome all limitations. After all, they stripped the divine of their titles, turning gods into Dungeon Lords and their domains into Dungeons. The department will give Nox the tools to achieve his ambitions, and his limitations will push him to the forefront of arcane discovery. More immediate challenges remain, though. Nox lacks the means to pay the university's ridiculous tuition. Only alchemy and smart business deals will earn him the hundreds of gold coins he needs.
Royal Road4.56· 575Goodreads4.29· 682
AlchemyAnti-heroCraftingCultivationDungeon CrawlingLitRPG+3

Brewing Bad

DWinchester

C45/100
Lucas is a dick, but you would be too if you died in a meth lab explosion and found yourself in a fantasy world. Now, with only his ruthlessness and an ever-increasing body of alchemical knowledge, he has to make his way in this new world — because being poor sucks no matter where you are. He has no idea what's going to happen, but he isn't dying again, because he already knows the afterlife is pretty much bullshit.
Royal Road4.50· 605
AlchemyAnti-heroBase BuildingCraftingGameLitGenius MC+3

The Saga of Keres

Lucian T. Einar

D40/100
1897. As the world teeters on the edge of war, Volundr — Ambassador of the Society of Nations — assembles a diverse group of individuals with extraordinary abilities. Among them: Steve, a devoted single father searching for his missing lover, and his mischievous daughter Alice. Others seek redemption, vengeance, or simply a place to belong. Cursed and desperate for answers, they agree to assist Volundr in exchange for his teachings on thaumaturgy and alchemy. Their first mission takes them to the Unseen City, under the threat of a devastating terrorist attack — where the most powerful thaumaturgist the world has ever seen has plans of her own. An alternate-historical fantasy set in the late 1890s, where magic clashes with science, kaiju roam the earth, and an unlikely band of heroes must confront forces both seen and unseen.
Royal Road4.59· 130
AlchemyAnti-heroGenius MCMilitaryOverpowered MCReincarnation+4

Rules of Biomancy: A LitRPG Healer Fantasy

Buller

D39/100
For almost half a century, Elijah kept his Core sealed — staying in the shadows, running a small alchemy shop on the outskirts of the slums, staying weak but staying safe. When he finds two people half-dead in an alley, both too young to have had a chance at life, he removes the chains from his magic to help them. An older MC with plant-based magic steps back into the light, taking on the role of teacher to two otherworlders given a second chance. A story of political drama and light LitRPG elements set in a secondary world.
Royal Road4.53· 494
AlchemyBase BuildingGameLitIsekaiLitRPGOlder MC+2

Hunting and Herbalism

Leif Roder, Synonymoose

D37/100
Zalia Taori is well equipped for life in the remote forest valley she calls home. But while tracking a deer through her snowy stomping grounds, she stumbles across a warp in the fabric of reality and is torn into an unfamiliar land where she must learn to survive as both predator and prey. As Zalia explores this forbidding new terrain, she encounters peculiar herbs, terrifying monsters, mysterious rituals, and some unexpected friends. She enters a world of classes and levels — where making the right move can bestow new powers, and a high-ranking bunny can be a formidable opponent. Just as this lone hunter gets her bearings, she spies opposing armies gathering their forces.
Goodreads4.14· 730
AlchemyClass SystemIsekaiLitRPGSecondary WorldStats+1

The Science of Cultivation

randombluecat

F24/100
Reincarnated into a world of cultivation, scientist Langley Seiker no longer has to dream about immortality — it's now possible. Except he has no talent. Through a chance encounter, he gains access to his familiar laboratory, which allows him to systematically study the mechanics of cultivation. Other cultivators ponder how to advance to the next realm. Langley cracks it with science — systematically unraveling not only how to cultivate, but also how to refine pills and inscribe talismans.
Goodreads4.19· 274
AlchemyBase BuildingCraftingCultivationGenius MCReincarnation

The Apprentice of Ouroboros

Magius Swiftscale

F21/100
Hated by humans. Hunted by monsters. Neska will prove that strength comes from more than defeating foes. Neska Aksen knew early on she was different from other snakes — spending her days giving mice big hugs and reading her witch's tomes in a rustic potion shop. A test ritual unlocked her Interface, revealing that she had a prior life as a human, and the power of Classes and monsters. Her power is unprecedented, but the monsters who fear the Awakened soon learn of her and her witch, forcing her to flee toward Rivilat Academy of the Awakened. With little to go on but steadfast determination and powers from both halves of her soul, Neska must find allies and gather power to survive — and decide what direction her own soul pulls her toward: humanity, or those they're supposed to be fighting against.
Royal Road4.47· 290
AlchemyCozyCraftingGenius MCLitRPGNon-human MC+5

The Alchemy Empress: 10,000 Years Later

LTKnight

F8/100
After ten thousand years perfecting a single pill in seclusion, Bai Fanxian emerges to find the world transformed. Cultivation is now rare and weak, true alchemy has faded into legend, and nobody alive knows what the masters of the past were capable of. Armed with ancient mastery and unmatched power, she sets out to remind everyone exactly why "Alchemy Empress" was once the most revered title in the cultivation world.
Royal Road4.04· 200
AlchemyCompetent MCCozyCultivationIsekaiOverpowered MC+4

A Balanced Path

BR Santiago

?
Terra conquered the solar system during a century-long golden age, then lost it all when Mana arrived. As humanity scrambles to rebuild with mana-based technology, strange elven invaders from beyond overwhelm every defense with their cultivation. Axl lost everything to those elven cultivators — his lunar mining station home, his entire family. He fought back, killing his way into one final desperate mission: a last stand that became a fresh start when crumbling lunar forces implanted him behind enemy lines inside an elven body. Now in a strange world of abundant Mana and a pervasive System, surrounded by elves and sentient beasts in the ruins of a city ravaged by undead, Axl must navigate cultivation in sword, alchemy, and the mysteries of the Dao — all in the hope of giving humanity a foothold in a war of extermination.
Royal Road4.52· 97
AlchemyCultivationIsekaiLitRPGMilitaryNon-human MC+4

Haley and Nana

M.C.A. Hogarth

?
When the system apocalypse hits, Haley is ready to become a wizard — but the system has other plans for her. A feel-good slice-of-life series following Haley Landry, her grandmother Nana, and the small town of Refuge as they navigate a cozy post-apocalyptic world with a game system imposed by magical aliens. Each installment is a short, warm read complete with a recipe.
Goodreads4.32· 136
AlchemyCozyCraftingDungeon CoreSystem ApocalypseWholesome